A young white girl, Lia Eltham, is left in Fu Manchu's care. A British regiment, chasing Boxer rebels, fires on Fu Manchu's home, killing his wife and child. When Lia Eltham grows up, he uses her as an instrument for revenge, killing all descendants of those who killed his family. Opposing Dr. Manchu are Police Inspector Nayland Smith and Dr. Jack Petrie.
