Holby City

On a new year road trip to compete for funding, Jac, Ric and Sacha confront some old enemies. Serena's worst fears are realised.

Nicky and Cameron compete when Jac offers one of them an opportunity for a promotion.

Cameron bites off more than he can chew when he clashes with Jac.

Frieda's hard-won contentment is abruptly shattered when Roman reappears. Xavier strains his relationship with Donna.

When Holby is stretched to breaking point, an angry Ric can't take the status quo any longer. Can Frieda suppress her pain by throwing herself into her work schedule?

Can Ange convince her patient to proceed with a life-saving operation? A resolute Ric campaigns for change. Does Nicky have the strength to fight for what she wants?

As Holly's condition weighs on Ange, a heartbreaking decision divides Holly's family. A smitten Cameron sets out to impress new locum Chloe.

Zosia returns to Holby, while a frustrated Jac tries to track down Frieda. Ange admits there is no hope for her patient Holly, but will her parents agree?

Zosia's big news gets a mixed response, and her situation is further complicated when a colleague from the US turns up. Sasha is rattled when an old flame appears on the ward.

A computer virus shuts down Holby’s power. Jac and Connie fight to save the lives of close friends. As the hospital is evacuated, Ric mounts a desperate rescue for a trapped Essie.

Ric battles to control Kofi’s anger when he arrives at Holby with Darla. Frieda returns to Darwin ready to lose herself in work, only to be paired with a Zosia for the day.

Fletch worries there may be more to Theo’s disappearance than meets the eye. Donna meets Xavier’s mother for the first time, but things don’t go as smoothly as expected.

Ange uncovers a long-buried secret that threatens to completely shatter her world. Can Frieda manage to work within the rules when a friend of Roman’s appears in Holby?

Chloe is wrongfooted when ex-boyfriend Evan unexpectedly turns up on Darwin Ward, and Dom is confronted with life-changing revelations.

Dom throws himself into work as he struggles to process a shocking family secret. Zosia undermines Jac’s authority and puts a strain on their already fraught relationship.

A startling incident forces Zosia to reconsider her future at Holby, Cameron has to treat a close relative of Xavier's, and Dom tries to keep Carole at arm's length.

Jac’s top-dog status is challenged when a talented new surgeon causes a stir. Donna is flattered to be offered a new career opportunity.

Kian’s big personality begin to grate on Jac. Ange opens up to Dom, revealing a big secret about Chloe. When Sue makes a big mistake, Donna tries to limit the damage.

Ange plans to tell Chloe her biggest secret, and Ric’s granddaughter arrives at Holby, forcing Ric to deal with her pregnancy head on.

Struggling with the news that Dominic is her half-brother, Chloe is forced to operate with him. Lofty returns to Holby with a secret.

Dominic faces his difficult past when he goes head to head with his abusive ex, Isaac, while Ange and Carole band together to try to help him.

Will Lofty and Dom’s marriage survive under the pressure of Isaac’s presence at Holby, and is Sacha’s relationship with Patricia over before it’s even begun?

As Dom and Isaac grow closer, is Dom at risk of falling under his spell? Chloe gets an unpleasant surprise when she returns to work.

When Lofty is put in harm’s way, is Isaac’s fate sealed? In the hope of protecting Chloe, Cameron makes a selfless gesture.