Nang ang mahiwagang imbensyon ni Val Helsing ay nagkaloko-loko, si Drac at ang kanyang tropa ay naging tao at si Johnny ay naging halimaw! Sa magkapalit nilang anyo, si Drac at Johnny ay kailangang magtulungan para makahanap ng lunas. Sa tulong ni Mavis at ng tropang Drac, madalian ang paghanap ng paraan para maibalik sila sa dati kung hindi ay magiging permanente ang kanilang pagbabagong anyo.

When a legendary thief sets his sights on the Mona Lisa, he recruits two young strangers to help him - Chiara, an Italian cybercrime expert and Jay, a French explosives specialist - before revealing he is both their father. Thrown into a chaotic reunion, this new family must learn to work together and try not to kill each other if they want any chance at pulling off the heist of the century.