Forensic Files

A used tissue, 12 years after the murder of a young Missouri woman, may be what cracks the case with a suspect list a mile long.

The 1960 kidnapping and murder of brewery heir Adolph Coors III leads to one of the most intense manhunts in U.S. history.

An ammunition box and fluorescent fibers reveal the betrayal that led to the murder of a millionaire's family.

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.

In 1997, Kelly Eckart's car was found with her belongings still in it, after working the late shift in Franklin, Indiana. Days later, her body was found in an isolated ravine.

When a man dies after falling down the stairs, a witness says one thing and the evidence says another.

A murder in Australia baffles police, until they find a device intended to save lives is the only witness to the man's death.

DNA profiling reveals clues leading to a killer's identity 20 years later.

How the bombs were made leads investigators in Colorado to find the perpetrator.

A woman is abducted and a month later found dead, then a tip leads investigators in the right direction.

When a high school athlete is killed in a hit-and-run accident, investigators hoped tiny paint chips and shards of plastic would lead them to the driver.

The body of an insurance assessor is found in a river in Tampa, Fla.; a unique murder weapon and blatant clues lead the police straight to her careless killer.

Detectives discover new clues left by a stalker's letter to his victim.

A man states that a robber shot and killed his wife while they were on the beach, but a song he downloaded makes investigators suspicious.

The murder of 53-year-old Paul Gruber is examined, and the evidence points to Darryl Robin Kuehl, who was later convicted of the crime.

Tipster is found dead after revealing that a woman's death 16 years ago was murder.

For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.

A mussel diver and his fiancée are found dead in their burnt home; a tiny clue points to arson and murder.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.

A man calls for help when his wife has a fatal fall down the stairs; numerous amount of bloodstains make police suspicious.

A twelve-year-old girl claims that she was abducted and sexually assaulted; her story seems unbelievable until police discover fibers on her clothing.

The bomb was constructed to cause as much damage as possible, and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.