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A commuter ship capsizes, prompting a struggle for the staff to treat the influx of new patients while dealing with daring new employees take charge.

Dr Lenox and Dr Archer clash over new leadership roles in the ED while hospital-wide budget cuts force long‑time staff onto the chopping block.

Asher treats a woman whose undiagnosed condition threatens the lives of both her and her unborn child.

Amidst a familiar face's return, Ripley and Charles tackle a rare disorder case whilst Frost grapples with a lying father over his daughter's illness.

On Halloween, chaos ensues in the E.D. as Hannah assists a pregnant woman with an autistic son, while Charles and Jackie disagree on a psych case.

Chicago P.D. steps up Goodwin's security after she's threatened online by a former employee; Archer and Frost treat victims from a disciplinary camp.

Shocking information that conflicts with a patient's DNR is revealed by Ripley and Frost; Archer and Lenox's conflict reaches its breaking point.

Goodwin's troubles persist; Charles clashes with his former resident over a depressed patient; Lenox and Ripley treat a car accident victim.

The life of someone from the team is threatened. Frost and Abrams have a difficult time with their patient, and Asher deals with a religious patient.

An army of surgeons prepares to separate conjoined twins; Asher reconnects with someone from her past; Archer treats a boss with a heart problem.

Lenox's mentorship is put to the test; Asher helps a religious young woman with an ectopic pregnancy.

Following the subway tunnel collapse, Ruzek and Kidd treat injured passengers and track down the offender; Archer and Frost perform an amputation.

Goodwin struggles with the aftermath of her attack; Ripley treats a patient with helicopter parents; an ED staffer makes a career-ending mistake.

Gaffney gets a surprise visit; Asher and Naomi search for the cause of an infection; Lenox and Frost work together to save the victim of a shooting.

Ripley struggles to rescue a woman and her daughter trapped in an abandoned well; an old friend from Frost's TV days shadows Maggie.

When her former patient returns to Med, Goodwin learns that time doesn't heal; Frost and Charles treat a patient struggling with his sexuality.

Charles and Archer treat a heart transplant patient who believes his new heart doesn't want to be in his body; Lenox takes a personal day.

Hannah is faced with a tough call to save a life. As Naomi's last day at the ER, Archer tasks her with a patient to handle on her own.

Maggie and Goodwin's friendship is tested as tensions rise during the nurses' union's negotiations with the hospital.

The hospital faces a staffing crisis as the nurses stage a sick-out; Archer and Frost bet on who can discharge their patients first.

Maggie and Frost fight to get a pair of lungs for a young cystic fibrosis patient; Asher learns whether she can become a surrogate.

Goodwin is tasked with enforcing difficult cuts to hospital personnel; Charles' daughter is hospitalized after a car accident.