Les premières 48

In Birmingham, Detectives Mike Allison and Cynthia Morrow investigate the tragic case of a mother shot in her car while her three young children sat in the back seat. As detectives close in on a suspect, they are stunned to learn what triggered the shooting.

When a twenty-nine-year-old man and his paralyzed mother are shot to death in their apartment, Louisville detective Kyle Willett is called to the west side of town to lead the case. As the investigation unfolds, Willett and his team are shocked to learn what initiated the double homicide - a schoolyard fight between two teenaged classmates.

In Birmingham, Det. Eric Torrence investigates the death of a 24-year-old father-of-two shot in the street. 36 hours later Det. Cynthia Morrow is called out to the murder of a 27-year-old man found in an open field. While Torrence struggles to find anyone who will ID his suspects, Morrow runs into similar problems trying to locate the last person seen with her victim.

In Birmingham Det. Cynthia Morrow and the homicide team try to weave together the events of drug deal gone bad when two brothers from out of town get more than they bargained for. In Louisville Det. Kristen Downs leads the investigation of a possible gang-related shooting. But when no one is willing to talk, the team is forced to turn to forensic evidence to piece together the murder.

In Cincinnati, Detectives Matt Thompson and Doug Lindle are investigating the double homicide of a local hairdresser and his elderly neighbor, both stabbed to death and set on fire. When detectives discover that one of the victim's cars is missing, they begin following a twisted trail of clues they hope will lead to the killer.

In Harris County, Sgt. Craig Clopton and his team investigate the murder of man killed by a single gunshot while being robbed. With little evidence on the scene, they must rely on an eyewitness to help them identify their suspects.

À Louisville, une famille endormie se réveille sous une pluie de balles de mitrailleuse, laissant deux jeunes garçons blessés et un adolescent mort. En l'absence de témoins oculaires, le détective Mickey Cohn doit recourir à des méthodes d'investigations à l'ancienne.

À Louisville, le détective Carl Payne et la brigade criminelle enquêtent sur le meurtre d'un jeune homme abattu en pleine rue et en plein jour. Lorsqu'un témoin mène Payne à un suspect borgne, il est surpris.

À Louisville, le détective Rick Arnold est touché de près lorsqu'il apprend que la victime de sa plus récente affaire de meurtre est le frère d'un bon ami.

In Harris County, a family is devastated when their teenaged son is shot and killed after a confrontation outside of a high school party. After interviewing the party patrons, Sgt. Wayne Kuhlman and his team learn that the victim may have been mistaken for a local gang member based on the color of an item of clothing he was wearing.

À Louisville, le détective Corey Cadwell et son équipe enquêtent sur le meurtre d'un père de famille de 28 ans poignardé à mort alors qu'il travaillait dans un bureau de tabac.

À Miami, le détective Rolando Garcia enquête sur la mort par balle d'un sans-abri local, connu pour s'occuper de ses amis de passage.

In Birmingham Detective Chris Anderson returns to his childhood neighborhood to investigate the murder of a man killed over ten pounds of marijuana.

Dans le comté de Harris, le sergent Roger Wedgeworth enquête sur l'horrible meurtre d'un sans-abri retrouvé poignardé à mort le long de l'autoroute Interstate 45. Sans témoin ni mobile, les enquêteurs se dépêchent de trouver un suspect avant que l'affaire ne soit classée.

Lorsque des morceaux de corps démembrés sont retrouvés flottant dans la baie de Biscayne à Miami, le détective Orlando Silva et l'équipe des homicides de Miami se mettent au travail jour et nuit.

À Louisville, la communauté est indignée lorsqu'un couple marié est abattu chez lui devant leurs deux jeunes enfants.