After losing his family and watching his younger sister become a demon, Tanjiro Kamado joins the Demon Slayer Corps to avenge them. The leader of the Twelve Kizuki captures Lady Tamayo after Ubuyashiki's attempt to stop him fails, plunging Tanjiro, Zenitsu, Inosuke, and the Hashira into the demons' stronghold, the Infinity Castle. Now, they must face off against some of their most powerful foes.

都会で生き抜くスキルに長けたネイサン・ドレイク（トム・ホランド）は、ベテランのトレジャーハンター、ビクター・"サリー"・サリバン（マーク・ウォールバーグ）から、500年前にフェルディナンド・マゼランが収集しモンカーダ家が失った財宝を探そうと誘われる。.