On their last night before embarking on separate life paths, best friends Jo and Raissa find a mysterious portal that transports them to Nakali, a mythical island filled with magical creatures they learned about from their Filipino families. As Jo and Raissa search for a way home, they discover their memories are at risk. Will they find a way off the island before they forget each other forever?

시즌 2・제임스 리스는 리스트를 모두 처리하고 삶의 새로운 목적을 찾으려 하지만, 정체불명의 세력으로 인해 모스크바에서 랭글리에 걸친 국제적 음모에 휘말리게 된다.