On their last night before embarking on separate life paths, best friends Jo and Raissa find a mysterious portal that transports them to Nakali, a mythical island filled with magical creatures they learned about from their Filipino families. As Jo and Raissa search for a way home, they discover their memories are at risk. Will they find a way off the island before they forget each other forever?

Saat Ali G mengetahui pacarnya selama ini hamil, dia mengakhiri istirahat 20 tahunnya dan pergi ke Amerika untuk merebut kejayaan lamanya.