Gulf Coast Bigfoot Research Organization (GCBRO) founders Bobby Hamilton and Jim Lansdale lead a team of commandos on a mission to find and kill a Bigfoot in order to prove its existence to science.

The GCBRO investigates a frightening Bigfoot encounter on a farm in the swampy Sabine River area. The hunters have a run-in with their old teammate-turned-rival Dr. Webb Sentell, a neuropsychologist and Bigfoot no-kill advocate.

The GCBRO responds to possible sightings of a dead Bigfoot and terrifying devil-monkeys. Controversy erupts over whether to kill or not at a Bigfoot gathering, and the crew have an exciting chase through the forest at night.

With new Bigfoot cases coming in every day, the GCBRO needs new hunters to keep up with the demand. A biker reveals a face-to-face encounter with Bigfoot in the woods, and the process of selecting new members culminates in a series of challenging tests.

Bobby and Brandi bring the GCBRO to help a lady whose home and pets have been attacked by Bigfoot. She's even taken some shots at the creature. An eyewitness leads the team to possible Sasquatch nests, and the hunt reveals some frightening encounters.

Don goes on a local TV show to reach out to the public about their Bigfoot sightings. The GCBRO travels to a rural area, where a family claims Bigfoot killed several of their dogs and attacked a young man. The hunt begins when another dog goes missing.

The GCBRO rushes in to help a young woman and her physically challenged husband who say they're being terrorized by Bigfoot pounding on the walls of their house. The team finds a huge handprint, twice the size of a human hand, in the mud.