Dr. Sandra Lee helps Melissa who has tried to cover a huge lipoma with a sweatshirt for years. Tyler's fear of cancer has kept him from having his head lumps diagnosed and Amber has ear keloids that have taken control of her life.

Dr. Sandra Lee assists patients including Ronen whose lump above his knee is one of the largest she has ever seen. Amber suffers from a debilitating skin disease, Sandy has a neck lump and Kristy's eyelid cyst is ruining her life.

Dr. Sandra Lee helps Anthony who has a facial cyst in an area called the triangle of death. Half of Mary's body is a size 18 while the other is a size 10 and Brandi's anxiety keeps her from getting a lump removed from her chest.

Dr. Sandra Lee assists Diane who has thousands of tumors all over her body, ruining her life. Will fears his shoulder lump will be ripped open at work, Anthony has a neck lump examined and Kal-Elle detests her varicose veins.

Dr. Sandra Lee helps Belinda whose lump on her neck causes her to be immobile. Nicole won't get married until she has her armpit lump removed, Adela is covered in wisdom spots and Nick foolishly removed a lipoma at home.

Dr. Sandra Lee helps Taylor who has a large bump at the base of her spine that is far more dangerous than she realizes. John jokes about a lump on his hip that's no laughing matter and Noelle has her stretched ears repaired.