Following many years of estrangement, twins Milo (Bill Hader) and Maggie (Kristen Wiig) have an unexpected reunion after a set of near-tragedies. The situation forces them to confront how their lives became so broken. For Maggie, it means examining why she's so unhappy in a marriage to a loving husband. For Milo, it means meeting with his first love to see if their romance can reignite. Eventually