Unorthodox profiler Will Graham is enlisted by the FBI's Jack Crawford to catch the Minnesota Shrike, a serial killer who targets young women. When answers prove elusive, they ask noted psychiatrist Dr. Hannibal Lecter to consult on both the case and the mental strain it is causing Will.

Will and Jack hunt a killer who is burying his victims alive as fertilizer for his intricate garden of fungus, while Hannibal tries to shield Will from prying tabloid journalist Freddie Lounds.

Determined to give Abigail closure, Will and Hannibal travel with Abigail back home to the scene of her father's crimes.

After the brutal murder of an otherwise happy family, Will and Jack uncover a string of child kidnappings where it seems the children have turned against their parents.

Determined to give Abigail closure, Will and Hannibal travel with Abigail back home to the scene of her father's crimes.

After the brutal murder of an otherwise happy family, Will and Jack uncover a string of child kidnappings where it seems the children have turned against their parents.

After a man is found dead in a hotel room with his kidney missing, Jack believes the serial killer known as the Chesapeake Ripper has resurfaced.

Will and Jack pursue a murderer who makes instrument strings from the gut of humans.

A human totem pole is found on a beach, comprised of seventeen different bodies. As the Team works to find a common thread between the victims, Abigail comes clean to Hannibal on a dark secret.

Will questions his sanity as he gets inside the mind of a killer who believes that she herself is already dead.

Having escaped custody, Dr. Abel Gideon seeks revenge on his former therapists, as Will battles his own escalating mental crisis.

Hannibal consults his own therapist about his complex relationship with Will, while Will's newly expanded theory on the Copy Cat killer makes Jack question his grasp on reality.

Will's mental decline results in tragedy, when it appears he may have murdered Abigail Hobbs. With himself as his only defender, Will desperately tries to prove he's being framed by the real Copy Cat killer.