House

House has recovered from multiple gunshot wounds and is back at work, taking on two cases simultaneously: Richard, paralyzed after brain cancer surgery eight years ago, who drove himself on his motorized wheelchair headfirst into a swimming pool; and Caren, a young woman paralyzed from the neck down after a yoga session.

House's ego has taken quite a blow because he failed to diagnose his last case, and it's affecting him physically. He is obviously in pain again, although he continues to deny it. House's new case is 7-year-old Clancy, a product of in-vitro fertilization, who's been admitted to the hospital with rectal bleeding and proclamations of being tortured by aliens.

The ketamine has worn off and House is back to using his cane and doesn't want to talk about it. His new patient is Ezra Powell (guest star Joel Grey), a renowned pioneer in the field of medical research, who collapsed in his lab. House puts Ezra through diagnostic rigors, but the team is unable to come up with a conclusive diagnosis, and Ezra's health continues to deteriorate.

House takes the case of Adam, a 10-year-old severely autistic boy who screams loudly for no apparent reason, at least not a reason his three previous doctors could diagnose. The team wonders why House is taking the case: the boy's not sick; his symptoms seem to be a product of his autism.

House takes on the case of 20-year-old female patient Tracy Dawson, who is rushed to Princeton Plainsboro Teaching Hospital with breathing difficulties and unexplained intense abdominal pain after she and her husband, Jeremy, are victims of a robbery.

A 600-pound man, George Hagel, is admitted to the hospital after he is found in his apartment in a coma. While they conduct the necessary tests, the team runs into several obstacles due to the sheer mass of the patient, and while sedated and undergoing an MRI, George suddenly awakes in a panic and struggles to get free. Upon awakening, George decides that he is fine and requests a discharge.

Kyle comes to the hospital regularly to visit his father, Gabe, who has been in a coma for 10 years. Noticing something "off" about Kyle, House conducts a mini-experiment that leaves the boy unconscious. When symptoms point to a possible genetic condition, House and his team must glean a family history from Kyle's only living relative: his comatose father.

House's newest patient is 18-year-old Jack (guest star Patrick Fugit, 'Almost Famous'), brought to the hospital after experiencing a heart attack and massive vomiting. Barely an adult himself, Jack has been the parent to his younger brother and sister since their parents died.

House and the team take on the case of Alice, a young girl with pancreatitis. Since her divorced parents can't agree on how to proceed with her treatment and won't let House bully them into making a decision, House's only option is to take them to court and let a judge rule on the matter.

It's Christmas at Princeton-Plainsboro and Wilson has a present for House: he and Detective Tritter have struck a deal and House has three days to accept it. Wilson will testify that he didn't sign the prescriptions House used to illegally obtain Vicodin, and House will receive two months in a rehab clinic for pleading guilty, avoiding jail time.

House is forced to respond in court to the criminal charges against him regarding illegal possession of narcotics, and the judge sets a date for a preliminary hearing. Enough is enough for Cuddy, who insists that House apologize to Detective Tritter as a final attempt to stay out of jail, since he refused to respond to Tritter's previous deal by the deadline.

House has beaten the drug charges and is back at the hospital after a short stint in rehab. Cuddy comes to collect on House's debt for perjuring herself on the stand and keeping him out of jail. She forces House to pay off the debt in clinic hours, requiring him to carry out a series of less-than-desirable patient exams in the clinic.

Sixteen-year-old Stevie Lipa is admitted to Princeton Plainsboro Teaching Hospital with a serious respiratory condition and internal bleeding. Oddities of his case land him under House and the team's care, but at the moment, House is irritated to learn that new hospital researcher Dr. Julie Whitner has been assigned his handicapped parking spot by the hospital entrance.

It's Valentine's Day at Princeton-Plainsboro and the ER is short-staffed due to a snowstorm. House encounters Foreman's latest patient, Hannah, who has sustained injuries from a car accident with her mother, Abby. House notices that despite her best efforts to act injured, Hannah is not feeling a bit of pain.

Patrick Obyedkov (guest star Dave Matthews), a 35-year-old musical savant, is in the middle of playing a piano concert when he suffers a painful involuntary muscle contraction in his left hand. After Patrick is admitted to Princeton-Plainsboro Hospital with a rare movement disorder, his case attracts the attention of Dr. House.

House is bewildered yet intrigued when he meets his newest patient, John Kelley, an ex-Marine who had saved House's life in a very realistic dream the night before. House is puzzled about how this man could have appeared in his dream before he met him.

A famous, 42-year-old, pregnant photographer, Emma Sloan (guest star Anne Ramsay), is brought to the hospital after suffering a stroke in the middle of a high-profile photo shoot with Tyson Ritter (All American Rejects). Although Emma's condition initially stabilizes, her health takes a turn for the worse when her kidneys inexplicably fail.

House and Cuddy board a flight back to the United States from Singapore, where they were speakers at an international conference. Shortly after takeoff, a passenger seated next to House becomes violently ill. While House brushes it off as a hangover, Cuddy suspects the man might have a deadly contagious virus and the other passengers could be at risk.

The team takes on the case of 6-year-old Lucy, who collapsed at daycare. They discover that the tissues surrounding Lucy's heart have hardened and are strangling her heart, a condition usually found in much older patients. As the team searches for an explanation, Lucy's condition worsens and she suffers a stroke.

The team takes on the case of Lupe, a young female scam artist who passes out while working a card-playing scheme on the streets. Lupe suffers from a lack of blood to the brain which had temporarily paralyzed her ability to make decisions or exercise free will.

Wilson prepares his 14-year-old leukemia patient, Nick, for a last-resort bone marrow transplant from his younger brother, Matty. With Nick's immune system completely wiped out from chemotherapy, Wilson is extremely cautious about keeping him healthy before the transplant. However, when Matty sneezes during a pre-op visit to his brother, Wilson knows that Matty is not healthy enough to donate.

Addie, a 19-year-old college student, is admitted to Princeton Plainsboro after coughing up a mouthful of blood during karate class. Before treating the patient, Foreman unapologetically informs the rest of the team that he is resigning, but will not say why. House strongly believes an infection is to blame for Addie's bleeding, even though her symptoms indicate otherwise.

Obnoxious 16-year-old chess prodigy Nate is admitted to Princeton-Plainsboro suffering from intense head pain that came on after he attacked his opponent during a speed chess tournament. Nate's mother tells the team that Nate has been having behavior problems ever since he became a teenager, and House suspects the behavior is a symptom of cluster headaches.

Cuban couple Esteban and his sick wife, Marina Hernandez, are pulled from the ocean during a dangerous rescue at sea while en route to the U.S. on a mission to reach Dr. House. Marina's medical records from Cuba were lost in the shipwreck, so the team runs a series of tests to determine the extent of her illness.