In the city of New Orleans, police officers, fire fighters, and emergency medical technicians working the overnight shift answer as many as a thousand emergency calls every night.

It's an emotional night on the Nightwatch in New Orleans as one EMS officer tells his partner that this is their last night on the job. Meanwhile, it's a tough night in a different way for the fire fighters as the group responds.

After a quiet beginning of the evening, multiple calls virtually explode across the radio at once--and the most alarming code heard is for "Officer Shot." The overwhelming response to that call leaves EMT's Titus and Dan to endure an agonizing wait.

Halloween provides a fitting backdrop to a night on the job that includes some chilling calls. Captain Kevin leads the fire fighters battling a blaze that's engulfed a house, and hopefully nothing more. Police officers Victor and Cedric hunt through.

Police officers Victor and Lejon join a SWAT team operation hunting a homicide suspect. The fire department tries to save a man who fell into the Mississippi River. And for the EMT's, the calls tonight are as much about comforting victims.

It's a full moon in New Orleans, and sure enough, all night long, the calls for the EMT's seem to get crazier and crazier: the victim of a machete hacking, the man whose finger is bitten off by a dog.

Randy and Justin chase down a suspected car thief, while both EMT teams respond to emergency calls involving children in distress.

Police officers pursue suspected drug dealers, while Keeley saves a group of partiers from a violent schizophrenic.

It's New Year's in New Orleans and gun violence is rampant as Police and EMS deal with armed robberies and shootings. Plus, EMT Gavin returns to the job, and everyone celebrates a new addition to the family.