A North Carolina teen is missing, and it's up to the family's private investigator to take a radical approach. Eighteen-year-old Nicole Martindale has run off with her dangerous outlaw boyfriend, and her mother is desperate to get her back.

The search for 15-year-old Alexandra Lowitzer leads her parents to a crack house in Columbus, Ohio. Meanwhile, in San Francisco, a family searches for the brother who vanished on a business trip.

In Arizona, the search for 16-year-old Dakota Kilpatrick leads to a bleak corner of Tucson. Meanwhile, in New York City, Doug and Cindy Putnam search for their son Robin, though it seems he may not want to be found.

A 15-year-old from Arizona is missing, and her parents believe a dangerous local family is behind it. Meanwhile, a popular Toronto-area schoolteacher vanished during an early morning jog.

A 16-year-old from Utah runs away from home, and her mother fears she may be selling herself to stay alive. Meanwhile, the renewed search for a missing Vancouver man leads to a remote island popular with outliers determined to live off the grid.

The search for a 15-year-old includes a sting operation and a sobering journey into a mining town’s illegal sex trade. Meanwhile, Don Biggers has spent the past six years searching for his wife, Pamela, who disappeared while on a business trip.