As Meredith and Cristina discuss their relationship woes at the Emerald City Bar, the bartender collapses.
2. Enough Is Enough (No More Tears)
This video is currently unavailable
October 1, 2005
44min
16+
When a family arrives at Seattle Grace Hospital after a serious car accident, Alex learns that their injuries are only the beginning of their problems.
3. Make Me Lose Control
This video is currently unavailable
October 8, 2005
44min
16+
Family secrets become public when Meredith's mother, who has Alzheimer's disease, is brought to Seattle Grace; frightening news about Cristina's health comes into the open.
4. Deny, Deny, Deny
This video is currently unavailable
October 15, 2005
44min
16+
Meredith’s mother has the hospital staff running in circles; Addison's involvement in the case of a cystic fibrosis patient could delay her departure.
5. Bring the Pain
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October 22, 2005
44min
16+
Meredith and Dr. Shepherd have to use more than medicine when a young woman's traditionalist, religious father forbids her to have a life-saving operation.
6. Into You like a Train
This video is currently unavailable
October 29, 2005
44min
16+
A train crash brings several seriously injured patients to the hospital, providing a distraction for Meredith as she awaits Derek's final decision.
7. Something to Talk About
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November 5, 2005
44min
16+
A male patient who seems to have a hysterical pregnancy fascinates the staff.
8. Let It Be
This video is currently unavailable
November 12, 2005
44min
16+
Derek and Addison's close friends come to Seattle Grace seeking radical surgery to avoid breast and ovarian cancer.
9. Thanks for the Memories
This video is currently unavailable
November 19, 2005
44min
16+
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit.
10. Much Too Much
This video is currently unavailable
November 26, 2005
44min
16+
A man who has priapism comes to the hospital, and Meredith awkwardly realizes that he is her one-night stand.
11. Owner of a Lonely Heart
This video is currently unavailable
December 3, 2005
44min
13+
Cristina Yang has little sympathy for an inmate (Rosanna Arquette), who jeopardizes her health to get out of solitary confinement.
12. Grandma Got Run over by a Reindeer
This video is currently unavailable
December 10, 2005
44min
16+
Burke and Yang disagree on how to treat a young boy who does not seem to want a needed heart-transplant.
13. Begin the Begin
This video is currently unavailable
January 14, 2006
44min
16+
Izzie cannot ignore the chemistry she shares with a patient awaiting a heart transplant; George treats Bex, a teenage hermaphrodite.
14. Tell Me Sweet Little Lies
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January 21, 2006
43min
16+
Meredith and Cristina lie to each other about their relationships; George must discharge an elderly patient who is no longer sick but refuses to leave the hospital.
15. Break on Through
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January 28, 2006
44min
16+
The nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves; an elderly patient's friends bring Meredith's mistake to light.
16. It's the End of the World
This video is currently unavailable
February 4, 2006
44min
16+
Meredith's premonition of having a bad day is realized when a medical case arrives threatening the lives of everyone in the OR.
17. As We Know It
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February 11, 2006
44min
16+
Despite the best efforts of the Seattle Grace staff, the code-black situation escalates.
18. Yesterday
This video is currently unavailable
February 18, 2006
44min
16+
Someone from Derek and Addison's past arrives in Seattle; Burke learns Christina's secret; Meredith looks into her family's dirty laundry after a visit with her mother.
19. What Have I Done to Deserve This?
This video is currently unavailable
February 25, 2006
44min
16+
Meredith and George find themselves at odds at work; Bailey, although technically still on maternity leave, finds herself treating Addison for an unusual feminine issue.
20. Band-aid Covers the Bullet Hole
This video is currently unavailable
March 11, 2006
44min
16+
It becomes a bad day for Christina when Bailey instructs her to take care of her baby; Derek and Addison come to terms with their relationship.
21. Superstition
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March 18, 2006
44min
16+
When a series of deaths occurs at Seattle Grace, the uncanny events bring out the doctors' superstitious sides and make Izzie nervous about Denny's surgery.
22. The Name of the Game
This video is currently unavailable
April 1, 2006
44min
16+
George begins to overstay his welcome; Meredith learns a secret about her father; Bailey gets back into a surgery room; Alex gets a lesson in bedside manners.
23. Blues for Sister Someone
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April 29, 2006
44min
16+
Izzie grills George about the personal details of his life; Addison takes Alex to task about a sensitive case, and Burke treats his musical hero
24. Damage Case
This video is currently unavailable
May 6, 2006
44min
16+
The interns care for a family involved in a car accident; Derek lets his emotions get the better of him; Burke and Izzie have a new suggestion for Denny.
25. 17 Seconds (Part 1 of 3 of Season Finale)
This video is currently unavailable
May 13, 2006
44min
16+
Finn offers a health update on Doc; Meredith must work with Callie for a day; George works with Derek; Burke and Izzie continue to search for a new heart for Denny.