Tick and Arthur go on their first patrol of The City, battle a bank robbing monstrosity, and attract the attention of AEGIS. Dot has a weird day. She and Overkill have a few drinks and compare plights.

The local AEGIS branch has reopened - Tick and Arthur tour the facility and take the hero test. Overkill and Dangerboat prepare to go back on the lam, but Dot intervenes. Superian encounters social media, and Miss Lint decides on a new villain strategy.

Tick and Arthur pursue the trail of the bank robbers into the gambling underworld. Overkill reconnects with an old mentor and learns his enemy The Duke may still be alive.

A strange bit of information sends Dangerboat in to lockdown. Dot frees Overkill of a burden and joins him on a mission. Meanwhile, Superian takes Arthur's advice - badly.

Tick e Arthur danno la caccia alla loro nemesi rapinatrice di banche nelle fogne, aiutati da nuovi amici superpotenti, ma Arthur deve affrontare questo nemico da solo. Dot e Overkill interrogano un mobile e scoprono uno dei segreti del Duca.

Tick and Arthur fight a beaurocratic battle to save an innocent creature from AEGIS experimentation. Dot tours an AEGIS open house, as Overkill visits an old friend.

Tick and Arthur, with the help of Tinfoil Kevin, confront the Donnelley brothers and rescue their precious hostages. Walter starts acting oddly. Dot and Overkill storm the Duke's lair.

Tick e Arthur devono prendersi cura di sei adorabili bambini nascondendoli da AEGIS. Joan e Kevin danno una mano. Superian viene inaspettatamente per una seduta di terapia.

Tick e Arthur si uniscono al Flag-5 e subiscono l'iniziazione con i loro compagni di squadra. Walter e Dot danno una svolta al sogno di Arthur che diventa realtà. Il Duca compie una mossa mortale su AEGIS.

The Tick, Arthur, Dot, and the rest of the family must battle The Duke and AEGIS itself. Miss Lint reveals her true goal and Superian weighs the pros and cons of accidental genocide.