After marrying Adrian (Gabby Concepcion), Lizelle (Angelica Panginiban) encounters her bratty stepdaughter, Ysa (Kim Chiu) who suddenly moves in with them. Ysa is dating Gary (Derek Ramsey) who is coincidentally Lizelle's ex-boyfriend. Past loves don't die as easy as Lizelle would think making her relationship with Ysa a crazy one. "I Love You, Goodbye" is a Filipino Star Cinema drama film.