Drugs, Inc.

San Francisco, Calif. ' the epicenter of the 1960s' psychedelic revolution ' is notorious for drugs. But in the new millennium, the city, especially the gay community, is struggling to recover from a meth epidemic.

Chicago, one of the biggest open-air crack and heroin markets in America, is at saturation point. It's an addict's dream as dealers compete with high purity drugs sold in very affordable quantities. The result: record levels of overdoses and homicides as gangs fight over drug turf. Go inside the deeply entrenched and violent world of the city's drug-corner industry.

In the Fifth Ward, a drug hub of Houston, Tex., see firsthand how drugs are dominating the area's economy and populous. We'll talk to a major crack cocaine dealer, a Hispanic street gang member, addicts, a pimp who claims to rule the streets and a full-patch member of the Aryan Brotherhood of Texas white supremacist prison gang.

In Denver, the cannabis industry is booming. With more medical marijuana dispensaries than Starbucks coffee shops, the city is fast becoming the U.S. capital of weed. In November 2012, Colorado went further, voting to allow the recreational use of marijuana, one of only two states to do so.

Modern Miami is a city largely built on the cocaine industry. Over four decades, the city has played an integral role in trafficking drugs from Latin America into the United States which has left the city with an insatiable narcotics appetite.

In Kensington, north Philadelphia, heroin, crack cocaine and PCP are dealt from a hundred different corners. Abandoned homes and factories serve as crash pads, shooting galleries, dope holes and stash houses. And for the fiends and dealers born in the neighborhoods, the area is a deadly trap.

Since the days of Kurt Cobain and grunge music, Seattle has been nicknamed Junkietown. The city's liberal laws and high demand for drugs is attracting gangsters and dealers looking to get rich. From the competitive crack business in Belltown to fashionable Molly users on the electronic dance music scene, this film explores the highs and lows of Seattle's drug business.

Phoenix, Ariz., is the wholesale drug capital of America, under the control of one of Mexico's most powerful and ruthless drug organizations ' the Sinaloa Cartel. Almost 200 miles north of the Mexican border, the city has become the major stopping off point for the large-scale distribution and transshipment of marijuana, heroin and methamphetamine up from Mexico and out to the rest of the country.

Music and drugs go hand in hand in Nashville. For musicians who don't make it, drugs are the easiest way to make a living. We talk to a user and freelance cook who makes methamphetamine at home to cover his costs and get high. Then, we'll learn how the 19th Judicial District Drug Task Force is faced with cleaning up after meth cooks operations that are both extremely dangerous and expensive.