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In the Season Four finale, after a massive bus accident left House without recollection of four hours prior to the accident, he and the team put the pieces of his memory together and discovered Wilson's girlfriend Amber was on the bus with him and was fatally injured. Wilson had to face the shocking realization that House was directly involved in Amber's death. As Season Five opens, with his ...
200924 episodes
16+
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Episodes

  1. S5 E1 - Dying Changes Everything
    September 15, 2008
    44min
    16+
    In the aftermath of Amber's death, Wilson announces his resignation.
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  2. S5 E2 - Not Cancer
    September 22, 2008
    44min
    16+
    The team investigates a string of mysterious deaths centering around a single organ donor, and House hires a private investigator to snoop on Wilson and the team.
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  3. S5 E3 - Adverse Events
    September 29, 2008
    44min
    13+
    A struggling artist falls ill and the team must use a discerning eye to uncover what may be hiding below the surface.
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  4. S5 E4 - Birthmarks
    October 13, 2008
    44min
    16+
    House gets back to his roots and a patient falls ill searching for her own.
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  5. S5 E5 - Lucky Thirteen
    October 20, 2008
    44min
    16+
    Thirteen's personal life is brought to the examining room table.
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  6. S5 E6 - Joy
    October 27, 2008
    44min
    16+
    The team treats a sleepwalking patient experiencing unexplained blackouts and Cuddy decides to adopt a newborn baby.
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  7. S5 E7 - The Itch
    November 10, 2008
    44min
    13+
    House and the team treat an agoraphobic patient who refuses to leave his home.
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  8. S5 E8 - Emancipation
    November 17, 2008
    44min
    16+
    A parentless teenager falls mysteriously ill and Foreman takes on a case of his own free from House's supervision.
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  9. S5 E9 - Last Resort
    November 24, 2008
    50min
    13+
    House and Thirteen are taken hostage by a man willing to kill for a diagnosis.
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  10. S5 E10 - Let Them Eat Cake
    December 1, 2008
    44min
    16+
    House and the team treat a fitness fanatic with a slimming secret.
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  11. S5 E11 - Joy to the World
    December 8, 2008
    44min
    16+
    House and the team ring in the holidays with a new medical mystery. Lori Petty Guest Stars.
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  12. S5 E12 - Painless
    January 18, 2009
    44min
    13+
    House treats a patient whose chronic pain pushes him to the edge.
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  13. S5 E13 - Big Baby
    January 25, 2009
    44min
    13+
    House tests Cameron's patience as the team takes on the case of a too-good-to-be-true teacher.
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  14. S5 E14 - The Greater Good
    February 1, 2009
    44min
    16+
    The team treats a former doctor who gave up her career in the pursuit of happiness.
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  15. S5 E15 - Unfaithful
    February 15, 2009
    44min
    13+
    A fake case becomes a real one as the team treats a priest whose past has taken his faith from him.
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  16. S5 E16 - The Softer Side
    February 22, 2009
    44min
    16+
    The case of a teenage patient with male and female DNA sends the team in different directions.
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  17. S5 E17 - The Social Contract
    March 8, 2009
    44min
    16+
    House and the team treat a patient who uncontrollably speaks his mind. Jay Karnes ("The Shield") Guest-Stars.
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  18. S5 E18 - Here Kitty
    March 15, 2009
    44min
    13+
    A woman who believes her cat has predicted her death desperately seeks House's help. Judy Greer ("27 Dresses") Guest-Stars.
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  19. S5 E19 - Locked In
    March 29, 2009
    44min
    13+
    A man injured in a bicycle accident is "locked in" his own body and needs the help of House and the team to save his life. Mos Def ("Be Kind Rewind") Guest-Stars.
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  20. S5 E20 - Simple Explanation
    April 5, 2009
    44min
    13+
    House and the team work to keep a husband and wife alive but are forced to make a difficult decision as both patients' conditions deteriorate. Meat Loaf Guest-Stars.
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  21. S5 E21 - Saviors
    April 12, 2009
    44min
    16+
    Cameron takes the lead when an environmental activist falls mysteriously ill.
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  22. S5 E22 - House Divided
    April 26, 2009
    44min
    13+
    House and the team treat a deaf teenager.
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  23. S5 E23 - Under My Skin
    May 3, 2009
    44min
    16+
    As House and the team try to diagnose a dying ballerina, House attempts to diagnose himself.
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  24. S5 E24 - Both Sides Now
    May 10, 2009
    45min
    16+
    House takes on a case of mind over matter as a patient's right and left brain struggle for dominance. Carl Reiner ("Ocean's Thirteen") Guest-Stars.
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Details

More info

Content advisory
Violencesubstance usealcohol usesmokingfoul languagesexual content
Subtitles
None available
Producers
Paul AttanasioDeran SarafianGreg YaitanesLawrence KaplowGarrett LernerThomas L. MoranDoris EganPeter BlakeGerrit van der MeerLeonard DickRussel FriendBryan SingerKatie JacobsGarret LernerEli Attie
Starring
Hugh LaurieLisa EdelsteinOmar Epps
Studio
NBCUniversal
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