Nobody knows what to make of May (Angela Bettis). Born with a lazy eye, for which she wore a patch while growing up, she became a loner oddball whose only friend was a perfectly kept doll. She moves to L.A. and takes up with a filmmaker (Jeremy Sisto), but the relationship sours quickly -- and dangerously. She then befriends an alluring lesbian colleague (Anna Faris), but that, too, along with every connection May attempts to make, turns deadly.