Car lover Dave has 17 huge, painful head bumps that concern his girlfriend and make him feel like a freak. Melissa recently moved to a new town but her mysterious red, scaly lesions cover her legs and steal her confidence.

John is a sweet guy trying to get over his bumpy past, but not as bumpy as the huge growth on his shoulder. Tami has yellow deposits on her eyelids that make it impossible for her to feel beautiful.

Angela has a huge, melon-sized growth on the back of her neck that she fears will ruin her daughter's wedding and her daycare business. Loretta is terrified that her painful, oozing skin condition will get in the way of making her movie.