While Santiago and Cristóbal overcome complications during a liposuction, anesthesiologist Pilar flirts with Cristóbal, and Santiago asks his partner to keep his personal life out of the clinic. Meanwhile, with Julia feeling like Santiago has no time for her or their son, Matías, Cristóbal supports them emotionally. And Cristóbal's outrageous actions lead to one of his former lovers stabbing him.

Santiago finds Cristóbal seriously injured by a former lover, Carmen, and in need of a rare blood type he shares with Matías. But the young man has run off with a girl. Julia chastises Cristóbal, and in return he prompts her to take control of her own life. Meanwhile, twins want surgery so they can each have an individual identity. Also, heartbroken by Cristóbal, anesthesiologist Pilar quits.

Julia researches how to continue her medical schooling. Surprisingly, Santiago discourages her, citing Matías's need for his mother. Meanwhile, the twins on whom the doctors recently operated are so shocked by the results that they attempt suicide. Also, with the financial situation of Ciruplastica becoming critical, Cristóbal tries to convince Santiago to take on a drug lord as a client.

Cristóbal escapes from criminals threatening harm unless he operates on a drug lord. Meanwhile, Julia looks for a job to pay her way through school. After Santiago fails to put more romance into his relationship, Julia shares her loneliness with Cristóbal. Matías is arrested for taking drugs at a party. While Santiago is distracted by family problems, Cristóbal schedules the drug lord's surgery.

Santiago prevents Cristóbal from operating on the drug lord and infuriates the man's gang by kicking them out. After Cristóbal reveals that the clinic is in dire shape financially, Santiago offers to sell the house he bought for Julia, who doesn't want it anyway. Matías becomes popular by dealing drugs. And Santiago is devastated to learn that he misdiagnosed a girl who has skin cancer.

The police find a hidden camera in Cristóbal's apartment. Meanwhile, Santiago finds out that the drug gang is following Julia and has kidnapped and beaten Cristóbal. He finally agrees to operate on the drug lord, but a man bursts into the clinic and interrupts the procedure. And Matías's drug dealing inadvertently causes an innocent bullied girl to get in trouble.

As the drug lord is prepared for surgery, a man bursts in and disconnects him from the machines, killing him. Santiago wants to quit the practice. Later, after Julia tries to reason with him, Santiago accuses her of being on Cristóbal's side. Meanwhile, while driving, Julia is chased, causing her to crash. And Matías comforts his classmate Lucia and steals Julia's money to pay his drug dealer.

After the incident with drug traffickers, patients cancel their appointments at the debt-ridden clinic. Cristóbal tries to create positive buzz with an interview, but the journalist humiliates him. When Santiago questions a patient's motives for huge breast implants, Julia asks if he thinks she herself should have breast surgery. Also, two girls from school offer to have a threesome with Matías.

Johanna catches Julia showing Cristóbal her breasts, and Cristóbal admits to Julia that he loves her. Santiago convinces a patient that getting implants just to please her boyfriend is wrong—and she thanks Santiago with a kiss. Santiago also has sex with the journalist Cristóbal spoke to. Meanwhile, Matías's encounters with his two female friends don’t go as planned.

To find out about Julia and Cristóbal's secret past, Catalina tries to seduce Cristóbal. Meanwhile, Julia and Santiago rush to the house where Matías was caught having a threesome, and they take different approaches to disciplining him. The doctors bring in a third partner to help the clinic stay afloat. And Carmen goes to the art gallery with a gun—but before she can use it, Cristóbal arrives.

Carmen arrives at the art gallery with a gun, but Cristóbal interrupts. Meanwhile, Matías gets more involved in drug dealing. Santiago surprises his wife with a homemade dinner but later has sex with a former patient. Cristóbal also has sex with the journalist who interviewed him. The new partner, Mauricio, botches a routine operation. Julia visits Carmen, thinking she is an art gallery client.

While holding Julia hostage, Carmen calls Cristóbal and threatens to hurt Julia. When he arrives, Carmen ties them both up and forces Cristóbal to declare his love for Julia. But when the police arrive, Carmen kills herself. Meanwhile, Santiago has sex with former patient Adriana again. Also, patient Lulu wants surgery so she can look like her cat. And Mauricio again proves to be a poor doctor.

When he finds out that Julia is okay after Carmen's attack, Cristóbal passionately kisses her. Santiago continues to receive calls from Adriana, whom Matías witnesses kissing Santiago. Later, Cristóbal vows to reveal the truth about his love for Julia, but before he can, he finds out that she is pregnant. Meanwhile, a drug dealer threatens Matías, who also angers his ex-girlfriend.

Corrupt Mauricio operates on Lulu, who wants to look like her pet cat, and he gives Botox injections to her rich female friends in exchange for sex. After Mauricio refuses to perform surgery on a badly burned boy because his mother can't afford to pay, Cristóbal insists that the clinic begin doing pro bono surgeries. Meanwhile, Lulu's friends are horrified to see the results of her surgery.

Realizing that Santiago still loves Julia, Adriana threatens to commit suicide. Mauricio starts treating prostitutes at the clinic. Santiago and Cristóbal tell him that he’s attracting the wrong kind of client. But Santiago regrets rejecting a transvestite patient. Meanwhile, Santiago and Julia argue over her pregnancy and plans for school. And Matías takes some of the drugs he is selling.

After Santiago saves a transvestite who almost dies due to an inept plastic surgeon, Santiago and Cristóbal vow to find out the identity of this "butcher." Eventually, Cristóbal is shocked to find out who the culprit is. Meanwhile, at a wild party, Mauricio touches the shocked Cristóbal seductively. And before telling Julia a secret, Catalina falls to her death from a terrace.

Cristóbal discovers the identity of the "butcher" surgeon, who was one of the best doctors at his college. Later, Cristóbal meets Kimberly at a bar and promises to make her more beautiful. Meanwhile, Matías's drug use gets his friends in trouble. Julia’s bed rest ruins her medical school plans. And Mauricio promises to operate on obese Liliana, ignoring warnings that she is mentally unstable.

Alicia really wants to tell Julia a secret that Catalina told her before dying, but Julia is too sick for more stress. Matías fears he has contracted a sexually transmitted disease. Kimberly becomes obsessed with Cristóbal. The doctors remove a huge hump from a woman's back. And Johanna is disappointed to discover that Alicia is not gay.

After finding out that Matías has a sexually transmitted disease, Julia agrees not to tell Santiago. Meanwhile, Santiago vows to return to maxillofacial surgery. When another patient was mistreated by the "butcher," Santiago has Professor Moreno arrested. Cristóbal tells Kimberly they can’t have a relationship. Mauricio almost rapes a clinic employee. And Julia has further pregnancy troubles.

When Julia has a miscarriage, Santiago blames her, and she kicks him out. Julia learns more about a night she was at Cristóbal’s, drunk, shortly before she got pregnant with Matías. Meanwhile, when Mauricio continues sexually harassing a clinic worker, the other doctors fire him. And Julia asks Cristóbal for the truth about what happened on that drunken night years earlier.

Cristóbal insists he and Julia only kissed on a drunken night years ago. Santiago asked Julia to marry him the next day, and soon the couple found out she was pregnant with Matías. But Julia collects Santiago's hair and Matías's blood for a DNA test. Matías is beaten up at school. A repeat patient, Glorita, causes trouble. And Santiago refuses to alter a man's face to resemble Michael Jackson's.

Revealing that a medical implement was left in her pelvis during surgery, Glorita demands a huge settlement. Meanwhile, Alicia is the only one who knows that Matías is Cristóbal's son, and she alters the DNA results. When Julia and Roco, a younger man from the college Julia’s now attending, arrive at her house to study, Santiago is waiting with a romantic dinner to convince Julia to take him back.

When Santiago tries to force himself on Julia, Matías steps in. Meanwhile, to prevent Glorita from suing, Cristóbal reluctantly seduces her. After refusing to operate on a man addicted to cosmetic surgery, Santiago quits his job and moves into a hotel. Also, Matías rejects Natalia and starts dating Johanna's daughter, Lucia. And Kimberly tires of Cristóbal using her only for sex.

Julia’s mother, Angelica, goes behind Julia's back, severely alters the divorce papers in her favor and presents them to Santiago. Meanwhile, Julia performs poorly her first few days back at school. Natalia sabotages Matías’s relationship with Lucia. Cristóbal is invited to a swingers' club and brings the reluctant Kimberly. And Cristóbal manipulates Santiago to get him to return to the clinic.

Although she realizes Cristóbal will always love Julia, Kimberly continues to date him. Cristóbal agrees to Julia's friend Roco interning at the clinic. Santiago has trouble adjusting to the bureaucracy at a public hospital. Matías and Julia worry about Angelica, who is behaving erratically. And transvestite Sofia Lopez returns seeking a sex change but hesitates after bonding with Johanna.