Kampioenen sluiten zich aan bij Johnny Cage in een meedogenloze strijd zonder grenzen om de duistere heerschappij van Shao Kahn te stoppen.

Harry and his girlfriend Marion dream of transcending their life of hustling and owning a store. While his mother is obsessed with TV and diet pills and envisions her chance to shine again on a game show. However, their dreams are shattered when their drug addictions begin spiraling out of control.