An aircraft piloted by James McCarthy (Dick Purcell) flying in the Caribbean runs low on fuel, and off course. McCarthy, hears a faint radio signal after crash-landing on a remote island. Passengers, Bill Summers (John Archer) and his black manservant/valet, Jefferson Jackson (Mantan Moreland) take refuge in a mansion owned by Dr. Miklos Sangre (Henry Victor) and his wife.
