Nancy has relocated to the border in search of a new life but she soon finds her past to be inescapable. Both problems and people follow her on her journey, but some have finally been left behind.

Nancy runs her first courier job for Guillermo across the border, but it doesn't go as planned. Meanwhile, Celia lives trough a tough time in prison, and Andy and his father Lenny face a confrontation on their family history.

Nancy successfully completes her first job as drug courier across the border. In the meantime, Celia closes a deal with Captain Till to get out of prison and Andy tries to fulfill his grandmother's death wish. However, Andy has to convince his family, especially his father Lenny, first.

When Doug's work in Agrestic is investigated, he abdicates from responsibility and takes refuge in Ren Mar where the Botwins sit shiva after Bubbie's death. After the week of mourning, Lenny decides to sell the house and Nancy and Andy run another errand for Guillermo.

Left behind in the desert by Nancy, Andy joins a group of immigrants to get back home while Nancy has to save Celia who's spy job for Captain Till got her into trouble. In the meantime, Silas and Shane battle with bees.

Nancy discovers something she shouldn't when she follows the tunnel in the back of the maternity shop. In the meantime, Isabelle moves to Celia when her father accepts a new job, Doug falls in love with a Mexican beauty he faces at the beach, and Silas flirts with Lisa.

Nancy speaks to her boss Esteban when Guillermo denies her cut of incoming pot. Meanwhile, Celia discovers cheap pharmaceuticals and Silas' relationship with Lisa deepens. Andy and Doug work on their human smuggling operation.

Nancy gets a deeper insight of Esteban when their date is forcibly interrupted. Lisa learns about Silas' pot growing activity, while Andy and Doug successfully smuggle illegal immigrants across the border. Celia's discovery of cheap pharmaceutical leads to an addiction.

Despite their busy schedules, Nancy and Esteban try to find some time for each other. After finding out about Shane's fantasies and Silas's new and much older girlfriend, Nancy also has to talk to both of her sons. With their relationship going on, Lisa and Silas add some special offerings to her cheese shop.

Nancy is shocked when she discovers another purpose of Esteban's tunnel. Celia's worried family intervenes and she is forced into rehab. Andy finds Doug's Mexican beauty Maria and brings her across the border. At home, Shane spends some time with his two new girlfriends.

Nancy find's parenting increasingly more difficult, Celia's rehab spirals downhill rapidly. Doug finds winning Maria's affections far more difficult than expected. Cheese sandwiches win the day but when the true nature of the tunnel is discovered Nancy is left with narrowing options, Roy Till is called.

Nancy decides to inform the DEA about the tunnel when she can't take the activities going on anymore. Celia works on her rehabilitation and make amends with her family. Andy falls for Maria and confesses to Doug.

After the tunnel bust, Nancy has to explain her involvement to Esteban. Celia starts looking for her daughter Quinn deep in Mexico, in order to make amends with her. Silas meets Lisa's ex-husband and Doug finds reason to stay alive.