Kishore (Srinivas Avasarala) is a filmmaker. He runs into professor Apparao Aggarwal (Shayaji Shinde) and comes to know the love story of Shyam (Varun Sandesh) and Anshu (Sanchitha Padukone.) But fate throws in a cruel twist in the form of Sunaina (Catherine Tresa.) What happens next? Will Kishore get that unique love story? That forms the story of Chammak Challo.