After a harrowing hostage incident left the night shift team badly shaken, everyone is finally back to business . . . everyone except T.C. Callahan (Eoin Macken), who has been temporarily suspended from the hospital after succumbing to a PTSD breakdown on the job. While the ER staff works to save a husband and wife who were impaled on the same piece of rebar in a freak motorcycle accident,...

When a rancher accidentally shoots his own wife, T.C. (Eoin Macken), Kenny (J.R. Lemon) and Paul (Robert Bailey Jr.) try desperately to save her, but it's too late. Before T.C. can come to terms with the loss of his patient, he's sent out to the scene of a crazy teenage ranch party. There, T.C. must perform a risky surgery in order to save the life of a young football star who has been impaled...

The night shift crew is put to the test when a teenage couple and a young pregnant woman land in the emergency room after a serious car crash. Topher (Ken Leung), TC (Eoin Macken), Jordan (Jill Flint) and Scott (guest star Scott Wolf) tend to the young couple, who had run off to get married against their parents wishes. As the girl's condition worsens, TC tries in vein to calm her distraught...

T.C. (Eoin Macken), Joey (guest star Adam Rodriguez) and Gwen (guest star Merle Dandridge) rescue an injured skydiver from the site of a near-fatal crash. Joey and Krista (Jeananne Goossen) counsel the skydiver's girlfriend after they uncover serious complications in the operating room. T.C., Topher (Ken Leung) and Ragosa (Freddy Rodriguez) treat an electrocuted janitor whose family gathers...

A patient's exposure to radiation sends the Night Shift into chaos. Topher (Ken Leung) implements an immediate quarantine and locks down the ER. Paul (Robert Bailey Jr.) cares for the quarantined patient with the help of Ragosa (Freddy Rodriguez) and Kenny (JR Lemon). Meanwhile, TC (Eoin Macken), Drew (Brendan Fehr), and Gwen (Merle Dandridge) race to the site of a multi-victim car cash,...

A thick fog in San Antonio strands T.C. (Eoin Macken), Jordan (Jill Flint) and Paul (Robert Bailey Jr.) far from San Antonio Memorial. Forced to use improvised methods to save the victims of a gruesome truck crash, the doctors soon discover that their patients are illegal immigrants led by a dangerous "coyote" guide – but the truth is even more complicated than they realize. Back at the ER,...

TC (Eoin Macken) ends up treating his own sister-in-law Annie (guest star Sarah Jane Morris, "NCIS") after she falls down a flight of stairs. The truth behind her fall turns out to be even more complicated than TC realizes, but Jordan (Jill Flint) isn't surprised; she knows some things about Annie's history that TC doesn't -- until now. Jordan joins Gwen (guest star Merle Dandridge, "The...

It's all hands on deck when a tremendous explosion sends dozens of casualties to San Antonio Memorial Hospital. Topher (Ken Leung) leads the team while Jordan (Jill Flint), Ragosa (Freddy Rodriguez) and Krista (Jeananne Goossen) treat the traumatized patients and their families. TC (Eoin Macken), Drew (Brendan Fehr), and Gwen (Merle Dandridge) race to the scene of the downtown explosion, where...

Drew (Brendan Fehr) finds himself in the middle of a shooting at a friend’s Army promotion ceremony and springs into action, disarming the shooter. Later, he has to treat his best friend's wife and finds that her bullet injury has revealed an even more severe medical condition. Topher (Ken Leung) and TC (Eoin Macken) treat a young woman whose chronic bouts of psychosis are becoming a danger to...

Jordan (Jill Flint) and Krista (Jeananne Goossen) rescue the victim of a motorcycle crash on a deserted rural road. Miles away from an ER, they improvise emergency medical care for the injured motorcyclist and rush him to the nearest operating room -- in a veterinary hospital. Back at the hospital, TC (Eoin Macken) and Paul (Robert Bailey Jr.) race to diagnose the cause of a teenager's...

TC (Eoin Macken) and Drew (Brendan Fehr) race to the scene of a building collapse during a rodeo. The badly injured and outspoken cowboy Shane (guest star Timothy Busfield) begins to exhibit strange symptoms while his girlfriend Lindsay Mayes (guest star Melissa Gilbert) struggles to make sense of it all. Paul (Robert Bailey Jr.) confronts Krista (Jeananne Goossen) about a patient who appears...

TC (Eoin Macken) introduces the night shift team to his MMA group therapy leader, Colonel Elwood "Smalls" Green (guest star, country music legend Trace Adkins), who surprises the group with a special greeting from the White House. Jordan (Jill Flint) and Paul (Robert Bailey Jr.) help a nine-year-old boy with a serious fever. When his high-strung mother begins to exhibit signs of distress as...

Drew (Brendan Fehr) and Paul (Robert Bailey Jr.) head to the scene of a multi-car collision. Paul takes a chance on a daring rescue and sustains injuries that could jeopardize his future as a surgeon. Back at the ER, the newly-anointed Dr. Ragosa (Freddy Rodriguez) along with Jordan (Jill Flint), Scott (Scott Wolf), Krista (Jeananne Goossen) and Kenny (JR Lemon), manage the deluge of...

TC and Scott (guest star Scott Wolf) unite to care for a comatose Jordan and her unborn baby. Drew (Brendan Fehr) and Gwen (guest star Merle Dandridge) are caught in a fire fight when a SWAT Team corners the two snipers. Meanwhile Dr. Joey Chavez (guest star Adam Rodriguez) scrubs back in for the night, and he calls into question his future with Krista (Jeananne Goossen). Ragosa (Freddy...

TC y Topher regresan de Afganistán para encontrar la vida de Jordan en riesgo y San Antonio bajo fuego mientras dos francotiradores mortales aterrorizar la ciudad.